A

B

C

FIGURE 3. Upstream promoter elements as determined by TfSiteScan for A₁ adenosine receptor in A human, B mouse and C rat. The aligned promoter regions from Figure 2 were used, on average about 624 bp in length. Upstream elements were listed in order by position and scored based on P-values for likelihood. Elements colored red, blue, and black are more likely to be possible promoter elements than green ones. The heavy cluster of elements in A and B at the first 100 bp indicate the SP-1 rich area; this is likely missing in C because those nucleotides are missing. Other elements of consensus between human and rodent are the FiTF-LFB2’, GATA-4, and GATA-1 sites. The murine and rat promoter elements have many similiar elements due to their high homology in DNA sequences.